Water → HCID 21920028, compound

Participants

Reaction Steps

A mixture of 10.0 g (64 mmol) 2-fluoro-4-nitrophenol, 130.24 g (70 mmol) 3-fluorobenzyl bromide and 17.6 g (127 mmol) potassium carbonate in 200 ml methyl-ethylketone is heated overnight at 80°. Water is added and the product is extracted with ethyl acetate, dried and evaporated. Recrystallisation from diethyl ether/hexane yields 12.68 g (75%) of a slightly yellow solid. MS: m/e=265.1 (M+).

Provenance & Evidence