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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884102Generated: October 27, 2026

Ammonium Hydroxide → N-[4-(4-Fluoro-benzyloxy)-phenyl]-malonamide

https://huagongshe.com/reaction/1884102

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium HydroxideHCID 14923—
ReactantN-[4-(4-Fluoro-benzyloxy)-phenyl]-malonamic Acid Methyl EsterHCID 10335957—
ProductN-[4-(4-Fluoro-benzyloxy)-phenyl]-malonamideHCID 1172243280%

Reaction Steps

The title compound is prepared in analogy to example 3 from N-[4-(4-fluoro-benzyloxy)-phenyl]-malonamic acid methyl ester and ammonium hydroxide. Yield: 80%. Colorless solid. MS: m/e=303.2 (M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06762320B2
Source datasetuspto-grants-2004_07
ORD IDord-4047a11073dc4081b1a1319ea29074d6
Source noteuspto-grants-2004_07