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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884104Generated: October 26, 2026

1-Nitro-4-{[4-(trifluoromethyl)benzyl]oxy}benzene → 4-(4-Trifluoromethyl-benzyloxy)-phenylamine

https://huagongshe.com/reaction/1884104

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Nitro-4-{[4-(trifluoromethyl)benzyl]oxy}benzeneHCID 2743792—
Reactant4-(3-Fluoro-benzyloxy)-phenylamineHCID 16775314—
Product4-(4-Trifluoromethyl-benzyloxy)-phenylamineHCID 2213788998%

Reaction Steps

Prepared in analogy to 4-(3-fluoro-benzyloxy)-phenylamine, by hydrogenation of 4-(4-trifluoromethyl-benzyloxy)-nitrobenzene. Yield: 98% of a slightly yellow solid. MS: m/e=268.3 (M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06762320B2
Source datasetuspto-grants-2004_07
ORD IDord-e9fc01687c4c4905a2a1b1b1e09de2c0
Source noteuspto-grants-2004_07