3-Fluorobenzyl bromide → HCID 21920014, compound

HRID 1884107Notes

Reaction equation

HRID 1884107 reaction equation
F[C:2]1[CH:3]=[C:4]([N+:17]([O-:19])=[O:18])[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[CH:11]=1.[F:20]C1C=C(O)C=CC=1[N+]([O-])=O.FC1C=C(C=CC=1)CBr>>[F:20][C:5]1[CH:6]=[C:7]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[CH:11]=2)[CH:2]=[CH:3][C:4]=1[N+:17]([O-:19])=[O:18]

Participants

4

Reactant 3

HCID 680073-Fluorobenzyl bromideHCID 5209483-Fluoro-4-nitrophenolHCID 21920028HCID 21920028, compound

Product 1

HCID 21920014HCID 21920014, compound

Procedure

Prepared in analogy to 3-fluoro-4-(3-fluoro-benzyloxy)-nitrobenzene, starting from 3-fluoro-4-nitrophenol and 3-fluorobenzyl bromide. Yield after recrystallisation from diethyl ether/hexane: 100% of a white solid. MS: m/e=265.0 (M+).

Workup

  1. customYield
  2. customafter recrystallisation from diethyl ether/hexane

Sources & evidence

ORD record
ord-92a68eacedfb450791f85f768308c2c4
Source dataset
uspto-grants-2004_07
Patent number
US06762320B2

Reaction notes

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