3-Fluorobenzaldehyde → 4-[2-(3-Fluoro-phenyl)-vinyl]-1-nitro-benzene

HRID 1884154Notes

Reaction equation

HRID 1884154 reaction equation
C(OP([CH2:9][C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=1)(=O)OCC)C.[F:19][C:20]1[CH:21]=[C:22]([CH:25]=[CH:26][CH:27]=1)[CH:23]=O>>[F:19][C:20]1[CH:21]=[C:22]([CH:23]=[CH:9][C:10]2[CH:11]=[CH:12][C:13]([N+:16]([O-:18])=[O:17])=[CH:14][CH:15]=2)[CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 680093-FluorobenzaldehydeHCID 256065Diethyl 4-nitrobenzylphosphonate

Product 1

HCID 686145784-[2-(3-Fluoro-phenyl)-vinyl]-1-nitro-benzeneYield 82%

Procedure

Prepared in analogy to example 56b) from (4-nitro-benzyl)-phosphonic acid diethyl ester and 3-fluoro-benzaldehyde. Yellow solid. Yield=82%. MS: m/e=243.0 (M+).

Sources & evidence

ORD record
ord-b68168e1ab5c47038d551836e580e668
Source dataset
uspto-grants-2004_07
Patent number
US06762320B2

Reaction notes

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