Ammonia → HCID 22137980, compound

HRID 1884158Notes

Reaction equation

HRID 1884158 reaction equation
C[O:2][C:3](=O)[CH2:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)=[CH:10][CH:9]=1)=[O:6].[NH3:24]>CO>[F:22][C:19]1[CH:20]=[CH:21][C:16]([CH2:15][CH2:14][C:11]2[CH:12]=[CH:13][C:8]([NH:7][C:5](=[O:6])[CH2:4][C:3]([NH2:24])=[O:2])=[CH:9][CH:10]=2)=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 69006188HCID 69006188, compound

Product 1

HCID 22137980HCID 22137980, compoundYield 94%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared in analogy to example 3 from N-{4-[2-(4-fluoro-phenyl)-ethyl]-phenyl}-malonamic acid methyl ester and 7M ammonia in methanol. Yield=94%. Colorless solid. MS: m/e=301.1 (M++H).

Sources & evidence

ORD record
ord-6c3c90a7c0434f36986ed97bb19c603a
Source dataset
uspto-grants-2004_07
Patent number
US06762320B2

Reaction notes

Loading…