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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884298Generated: November 2, 2026

Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate → 2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-pentanoic Acid

https://huagongshe.com/reaction/1884298

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoateHCID 12073922—
ReactantHCID 178527961HCID 178527961—
Product2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-pentanoic AcidHCID 23508304—

Reaction Steps

Example 39 is prepared from 5-(4-pyridinyl)-1,3,4-oxadiazole-2-thiol and 1d using the procedure described for compound 20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06762198B2
Source datasetuspto-grants-2004_07
ORD IDord-77fd64dc1f3b4f08aacb21d753b135d5
Source noteuspto-grants-2004_07