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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884299Generated: October 26, 2026

Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate → 2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[(5-methoxy-benzimidazol-2-yl)thio]-pentanoic Acid

https://huagongshe.com/reaction/1884299

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoateHCID 12073922—
ReactantHCID 178488032HCID 178488032—
Product2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[(5-methoxy-benzimidazol-2-yl)thio]-pentanoic AcidHCID 23508253—

Reaction Steps

Example 41 is prepared from 5-methoxy-2-benzimidazolethiol and 1d using the procedure described for compound 20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06762198B2
Source datasetuspto-grants-2004_07
ORD IDord-64d4891184804eceba93f96e1591e298
Source noteuspto-grants-2004_07