HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Fluorotoluene-alpha-thiol → 2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[[(4-fluorophenyl)methyl]thio]-pentanoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Fluorotoluene-alpha-thiol | HCID 85171 | — |
| Reactant | Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate | HCID 12073922 | — |
| Product | 2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[[(4-fluorophenyl)methyl]thio]-pentanoic Acid | HCID 23508249 | — |
Reaction Steps
Example 51 is prepared from 4-fluorobenzylmercaptan and 1d using the procedure described for compound 20.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06762198B2 |
| Source dataset | uspto-grants-2004_07 |
| ORD ID | ord-56c14142d3c440778c242db20f189729 |
| Source note | uspto-grants-2004_07 |