Dichloromethane → HCID 9806949, compound

Participants

Reaction Steps

A mixture of 10 (0.10 g, 0.2 mmol), N, N-dimethylmethyleneammonium chloride (0.10 g, 5.3 eq) and CH2Cl2 (25 mL) was stirred under argon for about 2 h and diluted with water (5 mL). The layers were separated and the organic layer was washed with water (5 mL), dried (sodium sulfate) and evaporated to give 17 (clear glass). 1H NMR (DMSO-d6) 2.1 (m, 2 H), 2.22 (s, 6 H), 3.0 (m, 2 H), 3.3 (m, 1 H), 4.0 (m, 1 H), 4.79 (s, 2 H), 6.2 (d, J=7, 1 H), 6.8 (t, J=7, 1 (d, J=8, 2 H), 7.2-7.6 (m, 13 H), 10.31 (s, 1 H). MS m/e 529.65 (MH+).

Provenance & Evidence