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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884349Generated: October 27, 2026

Sulfur, trifluoro(N-methylmethanaminato)- → 4-(1-Ethyl-1-fluoro-propyl)-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]-pyrimidine

https://huagongshe.com/reaction/1884349

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfur, trifluoro(N-methylmethanaminato)-HCID 123203—
Reactant3-[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-pentan-3-olHCID 23505738—
Product4-(1-Ethyl-1-fluoro-propyl)-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]-pyrimidineHCID 23505747—

Reaction Steps

The title compound was prepared by reacting 3-[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-pentan-3-ol with dimethylaminosulfur trifluoride using the procedure described in Example 12.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06765008B1
Source datasetuspto-grants-2004_07
ORD IDord-20dea3db399846b7bf53b16f76de5bcd
Source noteuspto-grants-2004_07