4-Fluorobenzyl bromide → 1'-[(4-fluorophenyl)methyl]-9-methoxyspiro[3H-benzo[h][1,4]benzoxathiine-2,4'-piperidine]-5,6-dione

HRID 188448Notes

Reaction equation

HRID 188448 reaction equation
[Br:24][CH2:25][c:26]1[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:20]([cH:21]1)[C:10]1=[C:9]([C:8](=[O:22])[C:7]2=[O:23])[S:14][CH2:13][C:12]2([O:11]1)[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:20]([cH:21]1)[C:10]1=[C:9]([C:8](=[O:22])[C:7]2=[O:23])[S:14][CH2:13][C:12]2([O:11]1)[CH2:15][CH2:16][N:17]([CH2:25][c:26]1[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]1)[CH2:18][CH2:19]2

Participants

3

Reactant 2

HCID 680214-Fluorobenzyl bromideHCID 576618849-Methoxyspiro[naphtho[1,2-b][1,4]oxathiine-2,4'-piperidine]-5,6-dione

Product 1

HCID 576619131'-[(4-fluorophenyl)methyl]-9-methoxyspiro[3H-benzo[h][1,4]benzoxathiine-2,4'-piperidine]-5,6-dione

Sources & evidence

ORD record
ord-76b7e2f28a674599b901c93241e32af0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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