HRID1884532

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)c1ccc(F)c(CN(Cc2ccccc2)C(=O)[C@@H](CO)NC(=O)OCc2ccccc2)c1

HCID86588818

未命名化合物

结构：C[C@@H](NC(=O)OCc1ccccc1)C(=O)N(C)Cc1cc(C(=O)OC(C)(C)C)ccc1F

HCID86588819

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)c1ccc2c(c1)CN(Cc1ccccc1)C(=O)[C@@H](CO)N2

HCID54251532

未命名化合物

收率 34%

PROCEDURE

实验过程

According to the procedure of Preparation 4 (d), except substituting tert-butyl (R)-4-fluoro-3-[[[N-(benzyloxycarbonyl)serinyl]benzylamino]methyl]benzoate (1.58 g, 3 mmole) for the tert-butyl (R)-4-fluoro-3-[[[N-(benzyloxycarbonyl)alaninyl]-methylamino]methyl]benzoate, the title compound (0.39 g, 34%) was prepared as an off-white solid following recrystallization from EtOAc/hexanes: MS (ES) m/e 383.0 (M+H)+.