反应详情

温度

0 °C

Into a solution of 2,6-dichlorobenzenesulfonamide (7.8 g, 34.5 mmol) in 30 mL of concentrated sulfuric acid at 0°, nitric acid (1.74 mL, 41.4 mmol) was added dropwise. The mixture was stirred at 0° C. for 2 hours, then 200 mL of water was added to produce a precipitate. The resulting mixture was filtered. The white solid was collected, washed with water and dried in vacuo to give the desired product (7.17 g, 76%). 1H NMR (DMSO-d6):δ8.25 (s, 2H), 8.20 (d, 1H), 7.92 (d, 1H).

1. customto produce a precipitate
2. filtrationThe resulting mixture was filtered
3. customThe white solid was collected
4. washwashed with water
5. customdried in vacuo