HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chlorophenyl)acetic acid → N-[(4chlorophenyl)acetyl]-L-alanine Iso-butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chlorophenyl)acetic acid | HCID 15880 | — |
| Reactant | N-(3-methylpentanoyl)-L-alanine Isobutyl Ester | HCID 15481764 | — |
| Product | N-[(4chlorophenyl)acetyl]-L-alanine Iso-butyl Ester | HCID 15481765 | — |
Reaction Steps
Following General Procedure B and using 4-chlorophenylacetic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example 3 above), the title compound was prepared as a solid having a melting point of 111°-113° C. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06767918B2 |
| Source dataset | uspto-grants-2004_07 |
| ORD ID | ord-62fb7ed2e8b94361a727a31a7b17baea |
| Source note | uspto-grants-2004_07 |