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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884940Generated: November 1, 2026

3-Thiophenacetic acid → 2-((Thien-3-yl)acetamido]butyric acid iso-butyl ester

https://huagongshe.com/reaction/1884940

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Thiophenacetic acidHCID 23404—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-((Thien-3-yl)acetamido]butyric acid iso-butyl esterHCID 54265759—

Reaction Steps

Following General Procedure I above and using 3-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06767918B2
Source datasetuspto-grants-2004_07
ORD IDord-53229084b35b4b7f8dc670cb6f987027
Source noteuspto-grants-2004_07