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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884949Generated: October 29, 2026

Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/1884949

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneacetic acid, 2-fluoro-HCID 67979—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl EsterHCID 53643249—

Reaction Steps

Following General Procedure I above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06767918B2
Source datasetuspto-grants-2004_07
ORD IDord-5d7ee7e9eb204f8e94b89dfa96d56452
Source noteuspto-grants-2004_07