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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884950Generated: November 1, 2026

2-(4-Fluorophenyl)acetic acid → 2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/1884950

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluorophenyl)acetic acidHCID 9837—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl esterHCID 54144399—

Reaction Steps

Following General Procedure I above and using 4-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06767918B2
Source datasetuspto-grants-2004_07
ORD IDord-0d967010cd204cd5ab030e2701964f80
Source noteuspto-grants-2004_07