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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884969Generated: November 1, 2026

2-methylpropyl (2S)-2-aminopropanoate → N-[(3-phenyl-1,2,4thiadiazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1884969

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
Reactant2-(3-Phenyl-1,2,4-thiadiazol-5-yl)acetic acidHCID 22492184—
ProductN-[(3-phenyl-1,2,4thiadiazol-5yl)acetyl]alanine Iso-butyl EsterHCID 22894976—

Reaction Steps

Following General Procedure I above, and using (3-phenyl-1,2,4-thiadiazol-5-yl)acetic acid (CAS# 90771-06-5) and alanine iso-butyl ester prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06767918B2
Source datasetuspto-grants-2004_07
ORD IDord-442ccd7307db44a5b59a0ca70f0248bd
Source noteuspto-grants-2004_07