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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1884970Generated: November 2, 2026

m-Tolylacetic acid → N-[(3-methylphenyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1884970

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Tolylacetic acidHCID 12121—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylphenyl)acetyl]alanine Iso-butyl EsterHCID 53803690—

Reaction Steps

Following General Procedure I above, and using 3-methylphenylacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06767918B2
Source datasetuspto-grants-2004_07
ORD IDord-64e444ad1ce040c7b4e31af5937a692d
Source noteuspto-grants-2004_07