Cyclohexanone Oxime → Cyclohexyl acetate

Participants

Reaction Conditions

Reaction Steps

Cyclohexane (1 ml), t-butyl nitrite (1 mmol), N-hydroxyphthalimide (0.2 mmol), and acetic acid (1 ml) were placed in a flask and were stirred at 80° C. in an atmosphere of argon gas (1 atm=0.101 MPa) for 20 hours. The resulting reaction mixture was analyzed to find that cyclohexanone oxime, nitrocyclohexane, cyclohexanone, and cyclohexyl acetate were formed in yields of 16%, 10%, 3%, and 2%, respectively.

Provenance & Evidence