Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclohexanone Oxime | HCID 7517 | — |
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | Tert-Butyl nitrite | HCID 10906 | — |
| Reactant | Nitrocyclohexane | HCID 14285 | — |
| Reactant | 5-Chloro-2-hydroxy-1H-isoindole-1,3(2H)-dione | HCID 22178410 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Cyclohexane | HCID 8078 | — |
| Product | Cyclohexyl acetate | HCID 12146 | — |
Reaction Steps
Cyclohexane (1 ml), t-butyl nitrite (1 mmol), 4-chloro-N-hydroxyphthalimide (0.2 mmol), and acetic acid (1 ml) were placed in a flask and were stirred at 100° C. in an atmosphere of argon gas (1 atm=0.101 MPa) for 20 hours. The resulting reaction mixture was analyzed to find that cyclohexanone oxime, nitrocyclohexane, cyclohexanone, and cyclohexyl acetate were formed in yields of 26%, 4%, 4%, and in a trace amount, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06768023B2 |
|---|
| Source dataset | uspto-grants-2004_07 |
|---|
| ORD ID | ord-efef041c28d745adb04802bcd4219f6f |
|---|
| Source note | uspto-grants-2004_07 |
|---|
