Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclooctane | HCID 9266 | — |
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | Tert-Butyl nitrite | HCID 10906 | — |
| Reactant | Cyclooctanone, oxime | HCID 136841 | — |
| Reactant | HCID 11240629 | HCID 11240629 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Cyclooctanone | HCID 10403 | — |
Reaction Steps
Cyclooctane (1 ml), t-butyl nitrite (1 mmol), N-hydroxyphthalimide (0.2 mmol), and acetic acid (1 ml) were placed in a flask and were stirred at 80° C. in an atmosphere of argon gas (1 atm=0.101 MPa) for 20 hours. The resulting reaction mixture was analyzed to find that cyclooctanone oxime, nitrocyclooctane, and cyclooctanone were formed in yields of 55%, 5%, and 4%, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06768023B2 |
|---|
| Source dataset | uspto-grants-2004_07 |
|---|
| ORD ID | ord-811431c5734e41f390666a471fe8b2dd |
|---|
| Source note | uspto-grants-2004_07 |
|---|
