Docosanedioic acid → 9,10-Epoxy-18-hydroxyoctadecanoic acid

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Reaction Steps

The present invention provides a process for isolating, from outer birch bark, at least one of 9,10-epoxy- 18-hydroxyoctadecanoic acid; 9,16-dihydroxyhexadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid (phloionolic acid); 20-hydroxyeicasanoic acid; 22-hydroxydocosanoic acid; 18-hydroxyoctadec-9-enoic acid; docosandioic acid; and octadec-9-enedioic acid; comprising: (1) subjecting the outer birch bark to hydrolysis to provide a second outer birch bark and a second solution; (2) separating the second solution from the second outer birch bark; (3) condensing the second solution at a temperature below about 50° C. to provide at least one of 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,16-dihydroxyhexadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid (phloionolic acid); 20-hydroxyeicasanoic acid; 22-hydroxydocosanoic acid; 18-hydroxyoctadec-9-enoic acid; docosandioic acid; and octadec-9-enedioic acid.

Provenance & Evidence