Hydrochloric Acid → HCID 54028115, compound

Participants

Reaction Conditions

Reaction Steps

Into 210 ml of dry ether, 10 g of LiAlH4 was added, and under stirring, a solution of the above carboxylic acid in 70 ml of ether was added dropwise in 70 min. while keeping a temperature of 2°-6° C. after the addition, the mixture was raised in temperature to 23° C. and stirred for 3 hours. After standing for 12 hours, 5% hydrochloric acid was added to acidify the mixture while keeping a temperature of below 15° C., and the product was extracted with ether and washed successively with water, 5% NaOH aqueous solution and water, followed by drying with anhydrous MgSO4. By distilling off the solvent and effecting vacuum distillation, 10 g of (S)-4-octyloxypentanol was obtained as a fraction at 150° C./5 mmHg. The product showed the following IR data.

Provenance & Evidence