Hydrochloric Acid → HCID 14534035, compound

Participants

Reaction Steps

In a solution of 1.06 g (8.0 mmol) of 5-methoxyhexanol dissolved in 5 ml of pyridine, 1.83 g (9.6 mmol) of p-toluenesulfonyl chloride dissolved in 5 ml of pyridine was dropped at below 5° C. on an ice-water bath. The mixture was stirred for 6 hours at room temperature and then poured into 100 ml of cold water. The mixture was then acidified by 6N-hydrochloric acid and extracted with isopropyl ether. The organic layer was washed with water and dried with anhydrous magnesium sulfate, followed by distilling off the solvent to obtain 5-methoxyhexyl p-toluenesulfonate.

Provenance & Evidence