HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenol → HCID 10337083, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenol | HCID 403 | — |
| Reactant | 3-Butyryl-4-chloro-8-methoxyquinoline | HCID 11777567 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 10337083 | HCID 10337083 | 59.5% |
Reaction Steps
3-Butyryl-4-chloro-8-methoxyquinoline (2 g, 8 mmol), 4-aminophenol (1.24 g, 11 mmol) and 1,4-dioxan (50 ml) were heated at reflux for 2 hours, then the solid filtered off and converted to free base. Recrystallisation from ethanol and then methanol gave 3-butyryl-4-(4-hydroxyphenylamino)-8-methoxyquinoline (1.6 g), m.p. 270°-272°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05143920 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-e6043cd61ec14f2c886d5d7ab3aa442b |
| Source note | uspto-grants-1992_09 |