HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-2-chlorophenol → HCID 19880280, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-2-chlorophenol | HCID 77578 | — |
| Reactant | 3-Butyryl-4-chloro-8-methoxyquinoline | HCID 11777567 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 19880280 | HCID 19880280 | 34.4% |
Reaction Steps
3-Butyryl-4-chloro-8-methoxyquinoline (2.64 g, 10 mmol), 2-chloro-4-aminophenol (1.58 g, 11 mmol) and 1,4-dioxan (20 ml) were warmed briefly to reflux, cooled, and the solid filtered off. Recrystallisation from pyridine gave 3-butyryl-4-(3-chloro-4-hydroxyphenylamino)-8methoxyquinoline hydrochloride (1.40 g, 34%), m.p. 267°-269° (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05143920 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-4865e531a45544a781612cf4e702e660 |
| Source note | uspto-grants-1992_09 |