P-Anisidine → HCID 178450501, compound

HRID 1885184Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[CH:5][CH:4]=1.[C:10]([C:15](=[CH:21]OCC)[C:16]([O:18][CH2:19][CH3:20])=[O:17])(=[O:14])[CH2:11][CH2:12][CH3:13]>>[C:10]([C:15](=[CH:21][NH:7][C:6]1[CH:8]=[CH:9][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[C:16]([O:18][CH2:19][CH3:20])=[O:17])(=[O:14])[CH2:11][CH2:12][CH3:13]

Participants

Reactant 2

HCID 7732P-Anisidine

HCID 3359484Ethyl 2-butyryl-3-ethoxyacrylate

Product 1

HCID 178450501HCID 178450501, compoundYield 131.9%

Procedure

4-Methoxyaniline (25 g) and ethyl 2-butyryl-3-ethoxyacrylate (57 g) were heated together on a rotary evaporator (bath temp 100°) for 1 hour to give ethyl 2-butyryl-3-(4-methoxyphenylamino)acrylate (78 g) as an orange oil.

Sources & evidence

ORD record: ord-5c09687b75164ae59317f8c8569b8bd4
Source dataset: uspto-grants-1992_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05143920

Reaction notes

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