Acetic Anhydride → HCID 19880340, compound

HRID 1885217Notes

Reaction equation

HRID 1885217 reaction equation
[CH3:1][C:2]1([CH3:22])[C:11]([CH2:12][OH:13])=[C:10]([N:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]2=[O:20])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([NH2:21])[CH:8]=2)[O:3]1.[C:23](OC(=O)C)(=[O:25])[CH3:24]>N1C=CC=CC=1>[CH3:1][C:2]1([CH3:22])[C:11]([CH2:12][OH:13])=[C:10]([N:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]2=[O:20])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([NH:21][C:23](=[O:25])[CH3:24])[CH:8]=2)[O:3]1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 14857302HCID 14857302, compound

Product 1

HCID 19880340HCID 19880340, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A mixture of 1 g of 2,2-dimethyl-3-hydroxymethyl-4-(1,2-dihydro-2-oxo-1-pyridyl)-6-amino-3-chromene, 10 ml of acetic anhydride and 10 ml of pyridine is allowed to stand at 20° C. for 24 hours. The mixture is evaporated, and customary working up gives 2,2-dimethyl-3-hydroxymethyl-4-(1,2-dihydro-2-oxo-1-pyridyl)-6-acetamido-3-chromene.

Workup

  1. customThe mixture is evaporated

Sources & evidence

ORD record
ord-0b977a19161847069057d371a837cc95
Source dataset
uspto-grants-1992_09
Patent number
US05143924

Reaction notes

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