Potassium Carbonate → HCID 19880157, compound

Participants

Reaction Steps

A solution of 3,4-bis(p-methoxybenzyloxy)benzyl chloride (2.58 g: 6.47 mMol.), N-methylpiperazine (777 mg: 1.2 Eq.), and potassium carbonate (893 mg; 1 Eq.) in dimethylformamide (7 ml) is stirred at room temperature for 3 hours. The reaction mixture is filtered to remove solid and concentrated under reduced pressure. The residue is washed with n-hexane to give 1-(3,4-bis(p-methoxybenzyloxy)benzyl)-4-methylpiperazine. Yield: nearly quantitative.

Provenance & Evidence