HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 131717512, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | HCID 11390866 | HCID 11390866 | — |
| Reactant | HCID 14032023 | HCID 14032023 | — |
| Reactant | HCID 53651853 | HCID 53651853 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 131717512 | HCID 131717512 | — |
Reaction Steps
7β-Amino-3-chloromethyl-3-cephem-4-carboxylic acid p-methoxy-benzyl ester p-toluenesulfonate in dichloromethane is treated with triethylamine, 2-(2-t-butoxycarbonylamino-4-thiazolyl)-2-(1-t-butoxycarbonyl-1-methylethoxyimino)acetic acid, N-methylmorpholine, and phenyl dichloro phosphate to give p-methoxybenzyl 7β-[2-(2-t-butoxycarbonylamino-4-thiazolyl)-2-(1-t-butoxycarbonyl-1-methylethoxyimino)acetamido]-3-chloromethyl-3-cephem-4-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05143910 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-f99cd99ff87342acaf115130e62459b9 |
| Source note | uspto-grants-1992_09 |