HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxygen → 4-Formylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxygen | HCID 977 | — |
| Reactant | P-Toluic Acid | HCID 7470 | — |
| Reactant | Terephthalic Acid | HCID 7489 | — |
| Reactant | 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl acetate | HCID 265566 | — |
| Catalyst | Titanium | HCID 23963 | — |
| Catalyst | Cobalt(II) acetate tetrahydrate | HCID 61372 | — |
| Catalyst | Manganese acetate tetrahydrate | HCID 93021 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-Formylbenzoic acid | HCID 12088 | 70.6% |
Reaction Steps
In a 500-ml titanium autoclave, 15.36 g (0.113 mol) of p-toluic acid, 0.232 g (1.13 mmol) of N-acetoxyphthalimide, 0.79 mmol of cobalt(II) acetate tetrahydrate, 0.79 mmol of manganese(II) acetate tetrahydrate and 107 g of acetic acid were placed, the resulting mixture was stirred at 150° C. in an atmosphere of a mixture of oxygen and nitrogen gases (1:1) [4 MPa (gauge pressure)] for 1 hour and thereby yielded terephthalic acid in a yield of 70.6% with a conversion from p-toluic acid of 74.3%. A small amount of 4-carboxybenzaldehyde was by-produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07741514B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-cb38b3fb36194c619d259bebd6e01bb4 |
| Source note | uspto-grants-2010_06 |