Methyl carbazate → HCID 67842277, compound

HRID 1885326Notes

Reaction equation

HRID 1885326 reaction equation
[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:11][C:10]([CH3:13])([CH3:12])[CH:9]3[O:14][CH:8]3[C:7]=2[CH:15]=1)#[N:2].[CH3:16][O:17][C:18](=[O:21])[NH:19][NH2:20]>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:11][C:10]([CH3:13])([CH3:12])[C@@H:9]([OH:14])[C@H:8]([NH:20][NH:19][C:18]([O:17][CH3:16])=[O:21])[C:7]=2[CH:15]=1)#[N:2]

Participants

3

Reactant 2

HCID 80519Methyl carbazateHCID 108673602,2-Dimethyl-3,4-epoxy-6-cyanochroman

Product 1

HCID 67842277HCID 67842277, compound

Procedure

A similar procedure to Reference Example 5 was performed using 6-cyano-3,4-epoxy-3,4 dihydro-2,2-dimethyl-2H-1-benzopyran and methylcarbazate, and as a result, trans-6-cyano-3,4-dihydro-2,2-dimethyl-4-(2-methoxycarbonylhydrazino)-2H-1-benzopyran-3-ol was obtained, m.p. 174°-175° C. (recrystallized from hexane-ethyl acetate).

Sources & evidence

ORD record
ord-d6e138ba5b8249039fb31f6083f6f59c
Source dataset
uspto-grants-1992_09
Patent number
US05143936

Reaction notes

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