反应详情

Hydrazine (40 g) was dissolved in ethanol (100 ml) and was placed in a flask equipped with a condenser, a dropping funnel, a thermometer and a magnetic stirrer. A solution of the above pentenenitrile intermediate (b) (80 g) in ethanol (300 ml) was added with stirring at a rate that the temperature did not rise above 35° C. The reaction mixture was then gently refluxed for 90 minutes, the solvent was partially removed and the residue was treated with water. The product was filtered off and dried.

1. customwas placed in a flask
2. customequipped with a condenser, a dropping funnel
3. customdid not rise above 35° C
4. temperatureThe reaction mixture was then gently refluxed for 90 minutes
5. customthe solvent was partially removed
6. additionthe residue was treated with water
7. filtrationThe product was filtered off
8. customdried