Hydrazine → HCID 178441976, compound

HRID 1885344Notes

Reaction equation

HRID 1885344 reaction equation
[NH2:1][NH2:2].Cl[C:4]([C:10]([CH3:13])([CH3:12])[CH3:11])=[C:5]([C:8]#[N:9])[C:6]#[N:7]>C(O)C>[NH2:7][C:6]1[NH:2][N:1]=[C:4]([C:10]([CH3:13])([CH3:12])[CH3:11])[C:5]=1[C:8]#[N:9]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 13497266HCID 13497266, compound

Product 1

HCID 178441976HCID 178441976, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Hydrazine (40 g) was dissolved in ethanol (100 ml) and was placed in a flask equipped with a condenser, a dropping funnel, a thermometer and a magnetic stirrer. A solution of the above pentenenitrile intermediate (b) (80 g) in ethanol (300 ml) was added with stirring at a rate that the temperature did not rise above 35° C. The reaction mixture was then gently refluxed for 90 minutes, the solvent was partially removed and the residue was treated with water. The product was filtered off and dried.

Workup

  1. customwas placed in a flask
  2. customequipped with a condenser, a dropping funnel
  3. customdid not rise above 35° C
  4. temperatureThe reaction mixture was then gently refluxed for 90 minutes
  5. customthe solvent was partially removed
  6. additionthe residue was treated with water
  7. filtrationThe product was filtered off
  8. customdried

Sources & evidence

ORD record
ord-8792ab13897544d3847a1ae5393a7c93
Source dataset
uspto-grants-1992_09
Patent number
US05144015

Reaction notes

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