HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → Ethyl 3-(hexadecyloxy)-2-[(hexadecylthio)methyl]propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Hexadecanethiol | HCID 18015 | — |
| Reactant | Ethyl 2-[(hexadecyloxy)methyl]-2-propenoate | HCID 12971817 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 3-(hexadecyloxy)-2-[(hexadecylthio)methyl]propanoate | HCID 19764340 | — |
Reaction Steps
To a solution of 20 g of 2-[(hexadecyloxy)methyl]-2-propenoic acid, ethyl ester and 10 ml of triethylamine in 60 ml of ethanol is added 53 ml of hexadecyl mercaptan. This mixture is stirred overnight, then the solvents removed and the residue purified by HPLC [hexane:ethyl acetate (9:1)], to give 32.9 g of the desired compound as a white waxy solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05144045 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-f22920ae98884709a68a514ecc876f5b |
| Source note | uspto-grants-1992_09 |