HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 53707521, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | HCID 19764355 | HCID 19764355 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Sodium chloride; water | HCID 57417360 | — |
| Product | HCID 53707521 | HCID 53707521 | 77.9% |
Reaction Steps
To a solution of 500 mg of 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-3-ethyl-5-[(hexadecyloxy)methyl]-4,5-dihydroisoxazole in 10 ml of tetrahydrofuran is added 2.13 ml of 1M tetrabutylammonium fluoride in tetrahydrofuran. After 2 hours the reaction is poured into water, ether and brine. The organic layer is separated, dried and evaporated, to give 300 mg of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05144045 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-67c71112e4e245e2bcc799665da87fc7 |
| Source note | uspto-grants-1992_09 |