化工社化工社 化学情報印刷レポート · 研究参考用
Water → 1-Bromo-2-nonadecyne
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | Phosphorus tribromide | HCID 24614 | — |
| 反応物 | Nonadec-2-yn-1-ol | HCID 10967930 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 1-Bromo-2-nonadecyne | HCID 19764387 | — |
反応手順
A mixture of 18.8 g of 2-nonadecyn-1-ol, 110 ml of ether, 1.14 ml of pyridine and 5.7 ml of phosphorous tribromide in 25 ml of ether is heated at reflux for 2 hours, then stirred at room temperature for 2 hours, poured into water and washed with hydrochloric acid. The solution is evaported and filtered through silicon dioxide with hexane, to give 16.9 g of the desired product as a white solid, mp. 34°-35° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05144045 |
| 出典データセット | uspto-grants-1992_09 |
| ORD ID | ord-d43997f77f4a4e969eb81ee6f9dc6ef7 |
| 出典メモ | uspto-grants-1992_09 |