Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 86746122 | HCID 86746122 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 19764416 | HCID 19764416 | 72.5% |
Reaction Steps
A mixture of 16.3 g of 2-[(hexadecyloxy)methyl]-3-(phenylmethoxy)-4-methylbenzenesulfonate-1-propanol, 9.22 g of sodium azide and 130 ml of N,N-dimethylformamide is stirred at 80° C. for 3.5 hours and then at room temperature overnight. The mixture is poured into water and extracted with ether. The ether layer is dried and the solvent removed. The residue is purified by chromatography, to give 8.9 g of the desired compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05144045 |
|---|
| Source dataset | uspto-grants-1992_09 |
|---|
| ORD ID | ord-d1e29713a2714e06a996db9bdb355579 |
|---|
| Source note | uspto-grants-1992_09 |
|---|
