(+)-2-Octanol → HCID 22845783, compound

HRID 1885505Notes

Reaction equation

HRID 1885505 reaction equation
C[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4](OCCC)[N:3]=1.[CH3:15][C@H:16]([OH:23])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]>>[CH3:15][C@H:16]([O:23][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][N:3]=1)[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]

Participants

3

Reactant 2

HCID 2723888(+)-2-OctanolHCID 62702426HCID 62702426, compound

Product 1

HCID 22845783HCID 22845783, compound

Procedure

The same procedure followed for the methylpropyloxynicotinic acid was used employing 1(S)-methylheptanol as the starting alcohol. A quantitative yield of 6-(1(S)methylheptyloxy)nicotinic acid (2, where R2 is 1(S)-methylheptyl was obtained as a brownish solid. The material was used without further purification.

Sources & evidence

ORD record
ord-c014afc5497e4bccbec12d8c8f5d5196
Source dataset
uspto-grants-1992_09
Patent number
US05145601

Reaction notes

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