Potassium sodium tartarate → HCID 15086846, compound

Participants

Reaction Conditions

Reaction Steps

2.8 ml (9.8 mmol) of a 3.5 molar solution of sodium bis-(2-methoxyethoxy)-dihydroaluminate in toluene are added under nitrogen to a solution of 1.83 g (4.9 mmol) of the compound from Example 13 in 10 ml of dry tetrahydrofuran at 25° C. and the mixture is stirred overnight at 60° C. After cooling to 20° C., a solution of 10 g of potassium sodium tartrate in 20 ml of water is added dropwise cautiously and the mixture is extracted three times with 100 ml of ethyl acetate each time. The combined organic phases are washed once with saturated sodium chloride solution, dried over sodium sulphate and concentrated in vacuo.

Provenance & Evidence