化工社化工社 化学情報印刷レポート · 研究参考用
Betamethasone → Cortisone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Betamethasone | HCID 9782 | — |
| 反応物 | Betamethasone Sodium Phosphate | HCID 65478 | — |
| 生成物 | Cortisone | HCID 222786 | — |
反応手順
Eight rabbits of the New Zealand breed were used, weighing approximately 2 kg. In the right eye of each animal, 0.8 ml/week of Bentelan Depot (equivalent to 4 mg betametasone) were instilled for 4 weeks. The left eye was kept as control. The medicament, administered subconjunctivally, brought about an increase of the intraocular tension in the first week, reached its peak in the second week and then remained constant until the fifth week.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05145871 |
| 出典データセット | uspto-grants-1992_09 |
| ORD ID | ord-ed12391bc7ef41f78560f3533f2d9e73 |
| 出典メモ | uspto-grants-1992_09 |