5,6,7,8-Tetrahydro-2-naphthol → HCID 131717521, compound

HRID 1885573Notes

Reaction equation

HRID 1885573 reaction equation
[Cl:1][CH:2]([C:8]1[CH:13]=[CH:12][C:11]([C:14]#[N:15])=[CH:10][CH:9]=1)[CH2:3][CH2:4][N:5]([CH3:7])[CH3:6].[CH:16]1[C:25]2[CH2:24][CH2:23][CH2:22][CH2:21][C:20]=2[CH:19]=[CH:18][C:17]=1[OH:26]>>[ClH:1].[C:14]([C:11]1[CH:12]=[CH:13][C:8]([CH:2]([O:26][C:17]2[CH:18]=[CH:19][C:20]3[CH2:21][CH2:22][CH2:23][CH2:24][C:25]=3[CH:16]=2)[CH2:3][CH2:4][N:5]([CH3:7])[CH3:6])=[CH:9][CH:10]=1)#[N:15]

Participants

3

Reactant 2

HCID 143055,6,7,8-Tetrahydro-2-naphtholHCID 19025859HCID 19025859, compound

Product 1

HCID 131717521HCID 131717521, compound

Procedure

(Compound 25) was subsequently prepared by treating (compound 26) with 5,6,7,8-tetrahydro-2-naphthol as described for the preparation of (compound 3). Reflux time 2 days. M.p. 132° C.

Workup

  1. temperatureReflux time 2 days

Sources & evidence

ORD record
ord-1b921899b8fa45bfb2240cb2daf8883c
Source dataset
uspto-grants-1992_09
Patent number
US05145870

Reaction notes

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