Benzene → HCID 73656211, compound

Participants

Reaction Steps

A mixture of 0.4 g of crude (2RS,3SR)-2,3-epoxy-3-(5-chlorothiophen-2-yl)-propanal according to e) and 0.5 g of formyltriphenylphosphorane in 15 ml of benzene is stirred at room temperature for 4 hours. The clear solution is decanted off from the undissolved material and concentrated by evaporation. The residue is taken up in ether, decanted off from the undissolved material and again concentrated by evaporation. Chromatography with ether/hexane (2:1) on silica gel yields the title compound in the form of a pale-yellow solid.

Provenance & Evidence