Hydrochloric Acid → HCID 19879568, compound

Participants

Reaction Steps

In a similar manner to that described in the previous example, 89.96 g (0.5285 moles) of diphenyl ether and 122.7 ml (148.58 g, 1.057 moles) benzoyl chloride were dissolved in 1000 ml of o-dichlorobenzene. In 10-20 gram portions, 222 g (1.665 moles) of aluminum chloride were added under stirring. Hydrochloric acid generated during the reaction was swept out with nitrogen and neutralized with aqueous sodium hydroxide solution. After the complete addition of aluminum chloride, the temperature was slowly raised to 95°-100° C. and the reaction was allowed to proceed at this temperature for two hours. The reaction was subsequently cooled and allowed to continue overnight at room temperature. Afterwards, the reaction was precipitated into methanol, the product was isolated by filtration, and then the product was recrystallized with filtering from toluene (Melting point=164°-165° C. by standard melting point apparatus).

Provenance & Evidence