HCID 10967287, compound → 2,6-Dichloroaniline

HRID 1885707Notes

Reaction equation

HRID 1885707 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:12]=[C:13]([Cl:16])[C:14]=1[NH2:15])C(OCC(C)C)=O>O>[Cl:1][C:2]1[CH:3]=[CH:4][CH:12]=[C:13]([Cl:16])[C:14]=1[NH2:15]

Participants

3

Reactant 1

HCID 10967287HCID 10967287, compound

Product 1

HCID 118462,6-DichloroanilineYield 98%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
250 °C

Procedure

0.2 mole=55.2 g of isobutyl 3,5-dichloro-4-amino-benzoate were initially introduced into an autoclave together with 250 ml of water. The mixture was stirred at 250° C. for 2.5 hours and the reaction gas formed was continuously removed to maintain a pressure of about 40 bar. The product was recovered by steam distillation. 32 g of 2,6-dichloroaniline were obtained, corresponding to a yield of 98%.

Workup

  1. customthe reaction gas
  2. customformed
  3. customwas continuously removed
  4. temperatureto maintain a pressure of about 40 bar
  5. distillationThe product was recovered by steam distillation

Sources & evidence

ORD record
ord-774a74d03b97457880cf7680bd7e0c32
Source dataset
uspto-grants-1992_09
Patent number
US05145958

Reaction notes

Loading…