HCID 19879676, compound → 2,6-Dichloroaniline

HRID 1885708Notes

Reaction equation

HRID 1885708 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]=[C:15]([Cl:18])[C:16]=1[NH2:17])C(OC1C=CC=CC=1)=O>O>[Cl:1][C:2]1[CH:3]=[CH:4][CH:14]=[C:15]([Cl:18])[C:16]=1[NH2:17]

Participants

3

Reactant 1

HCID 19879676HCID 19879676, compound

Product 1

HCID 118462,6-DichloroanilineYield 127%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
250 °C

Procedure

49 g (0.174 mole) of phenyl 3,5-dichloro-4-amino-benzoate were initially introduced into an autoclave together with 200 ml of water. The mixture was heated to 250° C. and stirred at this temperature for eight hours. During the reaction, the reaction gas was let off continuously and a pressure of about 41 bar was established. The residue was steam-distilled, and 35.8 g of 2,6-dichloroaniline having a purity of 63% were obtained. This corresponds to a yield of 80%.

Workup

  1. customDuring the reaction
  2. customthe reaction gas
  3. distillationThe residue was steam-distilled

Sources & evidence

ORD record
ord-a9bd098e3dea42cfb60f6de6545b5ac3
Source dataset
uspto-grants-1992_09
Patent number
US05145958

Reaction notes

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