3,5-Dichloro-4-amino-benzoate → 2,6-Dichloroaniline

HRID 1885709Notes

Reaction equation

HRID 1885709 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([Cl:12])[C:10]=1[NH2:11])C([O-])=O>O>[Cl:1][C:2]1[CH:3]=[CH:4][CH:8]=[C:9]([Cl:12])[C:10]=1[NH2:11]

Participants

3

Reactant 1

HCID 69315913,5-Dichloro-4-amino-benzoate

Product 1

HCID 118462,6-DichloroanilineYield 80%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
250 °C

Procedure

0.2 mole=41.2 g 3,5-dichloro-4-amino-benzoate were initially introduced into an autoclave together with 250 ml of water. The mixture was heated to 250° C. and stirred at this temperature for eight hours. The product was then recovered by steam distillation. 26 g of 2,6-dichloroaniline were obtained in a purity of 99.8%, corresponding to a yield of 80%.

Workup

  1. distillationThe product was then recovered by steam distillation

Sources & evidence

ORD record
ord-8a54934bbb3345daa446f4755cede81a
Source dataset
uspto-grants-1992_09
Patent number
US05145958

Reaction notes

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