HCID 19879681, compound → HCID 19879683, compound

HRID 1885717Notes

Reaction equation

HRID 1885717 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]([C:22]2[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=2)[C:8]2[C:13](=[O:14])[NH:12][C:11](=[O:15])[N:10]([CH3:16])[C:9]=2[NH:17][C:18]=1[CH:19]([CH3:21])[CH3:20])=[O:5])[CH3:2]>ClCCl>[CH2:1]([O:3][C:4]([C:6]1[C:18]([CH:19]([CH3:21])[CH3:20])=[N:17][C:9]2[N:10]([CH3:16])[C:11](=[O:15])[NH:12][C:13](=[O:14])[C:8]=2[C:7]=1[C:22]1[CH:23]=[CH:24][C:25]([F:28])=[CH:26][CH:27]=1)=[O:5])[CH3:2]

Participants

3

Reactant 1

HCID 19879681HCID 19879681, compound

Product 1

HCID 19879683HCID 19879683, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

11.35 g (50 mmol) of 2,3-dichloro-4,5-dicyanobenzoquinone are added to a suspension of 19.4 g (50 mmol) of the compound from Example 10 in 1 1 of dichloromethane and the mixture is stirred at room temperature for 2 h. It is then washed three times with water, and the organic phase is treated with sodium sulphate and active carbon, filtered and concentrated to dryness. 17.5 g (91% of theory) of colorless solid remain.

Workup

  1. washIt is then washed three times with water
  2. additionthe organic phase is treated with sodium sulphate and active carbon
  3. filtrationfiltered
  4. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-b9e6054a503b448aadfc99f592746926
Source dataset
uspto-grants-1992_09
Patent number
US05145959

Reaction notes

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