1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 57047319, compound

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Reaction Steps

In a manner similar to that of Example 14, the title compound of Example 13 (0.80 g) was coupled to 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid in the presence of DBU and the product was subjected to catalytic hydrogenation to remove the benzyl group, yielding 0.16 g of the title compound as a solid, mp 268°-271° , [α]D20 -69.3°(DMSO). NMR data was the same as for the

Provenance & Evidence